2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137117
    15-keto-PGE1
    15-keto-PGE1 is an inactive Prostaglandin E1 (PGE1) metabolite. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation.
    15-keto-PGE1
  • HY-101723R
    Modecainide (Standard)
    Modecainide (Standard) is the analytical standard of Modecainide. This product is intended for research and analytical applications. Modecainide is a major metabolite of Encainide, which is an antiarrhythmic agent.
    Modecainide (Standard)
  • HY-G0003R
    Iloperidone metabolite Hydroxy Iloperidone (Standard)
    Iloperidone metabolite Hydroxy Iloperidone (Standard) is the analytical standard of Iloperidone metabolite Hydroxy Iloperidone (HY-G0003). This product is intended for research and analytical applications. Iloperidone metabolite Hydroxy Iloperidone (P88; Hydroxy Iloperidone) is an active reduced metabolite of Iloperidone (HY-17410). Iloperidone metabolite Hydroxy Iloperidone can be used for the research of schizophrenia.
    Iloperidone metabolite Hydroxy Iloperidone (Standard)
  • HY-159196
    1α,25-Dihydroxy-24-oxocholecalciferol
    1α,25-Dihydroxy-24-oxocholecalciferol is the C-24 oxidative metabolite of 1,25-dihydroxycholecalciferol.
    1α,25-Dihydroxy-24-oxocholecalciferol
  • HY-134611
    (2-Hydroxyethoxy)acetic acid
    (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine.
    (2-Hydroxyethoxy)acetic acid
  • HY-131257R
    Gefitinib impurity 1 (Standard)
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.
    Gefitinib impurity 1 (Standard)
  • HY-133980AR
    O-Demethyl Lenvatinib hydrochloride (Standard)
    Bamifylline (hydrochloride) (Standard) is the analytical standard of Bamifylline (hydrochloride). This product is intended for research and analytical applications. Bamifylline hydrochloride is a drug in the chemical class of xanthine that acts as a selective adenosine A1 receptor antagonist.
    O-Demethyl Lenvatinib hydrochloride (Standard)
  • HY-151930S
    8′-Hydroxy ABA-d8
    8′-Hydroxy ABA-d8 is the deuterium labeled 8’-Hydroxy ABA.
    8′-Hydroxy ABA-d<sub>8</sub>
  • HY-N11676
    6-Hydroxy-TSU-68
    6-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517). It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68.
    6-Hydroxy-TSU-68
  • HY-N16572
    5-endo-Hydroxyborneol
    5-endo-Hydroxyborneol is a hydroxylation metabolite of a monoterpene compound. 5-endo-Hydroxyborneol can be used as a drug intermediate to synthesize optically pure compounds.
    5-endo-Hydroxyborneol
  • HY-N15681
    β-Apo-10'-carotenal
    β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research.
    β-Apo-10'-carotenal
  • HY-164340
    Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP
    Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP (Compound 16) is a β-glucuronide-type linker precursor that couples with NeoDegrader P1 to synthesize the NeoDegrader P1-β-Glucuronide Linker Complex. Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP and its derived linker-payload complexes can be used for the research of acute myeloid leukemia.
    Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP
  • HY-N6683R
    15-Acetyl-deoxynivalenol (Standard)
    15-Acetyl-deoxynivalenol (Standard) is the analytical standard of 15-Acetyl-deoxynivalenol. This product is intended for research and analytical applications. 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells.
    15-Acetyl-deoxynivalenol (Standard)
  • HY-113472R
    N-Methyl-4-pyridone-3-carboxamide (Standard)
    3-Methyladenine (Standard) is the analytical standard of 3-Methyladenine. This product is intended for research and analytical applications. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
    N-Methyl-4-pyridone-3-carboxamide (Standard)
  • HY-142592S
    Clozapine EP impurity D-d8
    Clozapine EP impurity D-d8 is the deuterium labeled Clozapine EP impurity D.
    Clozapine EP impurity D-d<sub>8</sub>
  • HY-117580S
    16α-Hydroxyprednisolone-d3
    16α-Hydroxyprednisolone-d3 is the deuterium labeled 16α-Hydroxyprednisolone. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily.
    16α-Hydroxyprednisolone-d<sub>3</sub>
  • HY-N0894A
    (3R,5R)-Octahydrocurcumin
    (3R,5R)-Octahydrocurcumin (Compound 7) is gut microbial metabolite of Curcumin (HY-N0005). (3R,5R)-Octahydrocurcumin exhibits neuroprotective efficacy against Aβ25-35-induced cell damage in SH-SY5Y, and anti-inflammatory activity against LPS-stimulated mouse microglial BV-2.
    (3R,5R)-Octahydrocurcumin
  • HY-113519
    14R(15S)-EET
    14R(15S)-EET (14R(15S)-EpETrE) is an oxylipin and a metabolite of Arachidonic acid (HY-109590).
    14R(15S)-EET
  • HY-143941S
    Hydroxychloroquine EP impurity D-d5 dihydrochloride
    Hydroxychloroquine EP impurity D-d5 (dihydrochloride) is the deuterium labeled Hydroxychloroquine EP impurity D dihydrochloride.
    Hydroxychloroquine EP impurity D-d<sub>5</sub> dihydrochloride
  • HY-136124
    Cetilistat impurity 1
    Cetilistat impurity 1 is an impurity of Cetilistat. Cetilistat, an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively.
    Cetilistat impurity 1
Cat. No. Product Name / Synonyms Application Reactivity